Esketamine spray for treating depression 'not cost-effective'

Despite a need for new treatments for adults, it is also not clear how well the drug works long term, the healthcare watchdog NICE said.Despite a need for new treatments for adults, it is also not clear how well the drug works long term, the healthcare watchdog NICE said.

Esketamine is a form of ketamine that targets a chemical linked with learning and memory.

by NICE.

Following comments by experts and clinicians,

on the draft guidance for England and Wales has now been launched.

The nasal spray, which contains esketamine and is also called Spravato and made by Janssen, costs about £10,000 per course of therapy.

In the US, it was approved for sale last year as a treatment for depression despite concerns over a lack of adequate testing.

"There is a clear need for effective alternative treatment options for people with treatment-resistant depression," said Meindert Boysen, deputy chief executive and director of the centre for health technology evaluation at NICE.

But he said the consequences and costs of patients using the drug were still not understood.

NICE says it cannot recommend the therapy because it doesn't know if improvements in depression symptoms continue after treatment stops, and how much it would cost to offer repeated courses of treatment.

Read the full story at https://www.bbc.co.uk/news/health-54014522

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